BindingDB logo
myBDB logout

null

SMILES: OC(=O)c1[cH-]c([o+]n1)-c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=UADDGBIOHFWIDV-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061908   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kynurenine 3-monooxygenase


(Rattus norvegicus)		BDBM50061908
PNG
(5-(3-Nitro-phenyl)-isoxazole-3-carboxylic acid | C...)
Show SMILES OC(=O)c1[cH-]c([o+]n1)-c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C10H6N2O5/c13-10(14)8-5-9(17-11-8)6-2-1-3-7(4-6)12(15)16/h1-5H,(H,13,14)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.68E+3n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Kynurenine 3-hydroxylase.

J Med Chem 40: 4378-85 (1998)


Article DOI: 10.1021/jm970467t
BindingDB Entry DOI: 10.7270/Q24B30DT
More data for this
Ligand-Target Pair