BDBM50061920 4-(3-Nitro-phenyl)-4-oxo-butyric acid::CHEMBL138934

SMILES: OC(=O)CCC(=O)c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=VNDVLOPITGDGOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine 3-monooxygenase (Rattus norvegicus)	BDBM50061920 (4-(3-Nitro-phenyl)-4-oxo-butyric acid | CHEMBL1389...) Show SMILES OC(=O)CCC(=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C10H9NO5/c12-9(4-5-10(13)14)7-2-1-3-8(6-7)11(15)16/h1-3,6H,4-5H2,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of rat kidney Kynurenine 3-hydroxylase.				J Med Chem 40: 4378-85 (1998) Article DOI: 10.1021/jm970467t BindingDB Entry DOI: 10.7270/Q24B30DT
					More data for this Ligand-Target Pair