BDBM50061981 CHEMBL3394322

SMILES: CC1=C(C(NC(=O)N1)c1ccc(o1)-c1cccc(c1)C(F)(F)F)C(=O)OCc1ccccc1

InChI Key: InChIKey=LLYXWTHCDFPAKT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50061981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50061981 (CHEMBL3394322) Show SMILES CC1=C(C(NC(=O)N1)c1ccc(o1)-c1cccc(c1)C(F)(F)F)C(=O)OCc1ccccc1 |t:1| Show InChI InChI=1S/C24H19F3N2O4/c1-14-20(22(30)32-13-15-6-3-2-4-7-15)21(29-23(31)28-14)19-11-10-18(33-19)16-8-5-9-17(12-16)24(25,26)27/h2-12,21H,13H2,1H3,(H2,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Inhibition of mPGES-1 in interleukin-1beta-stimulated human A549 cells microsomal membranes assessed as reduction in PGE2 formation incubated for 15 ...				ACS Med Chem Lett 6: 187-91 (2015) Article DOI: 10.1021/ml500433j BindingDB Entry DOI: 10.7270/Q2474CJH
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