BDBM50061985 CHEMBL76121::{2-[1-(2-Amino-6-chloro-purin-9-yl)-meth-(E)-ylidene]-cyclopropyl}-methanol
SMILES: Nc1nc(Cl)c2ncn(\C=C3/CC3CO)c2n1
InChI Key: InChIKey=KKBVYTNBEFLMBF-GORDUTHDSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50061985 (CHEMBL76121 | {2-[1-(2-Amino-6-chloro-purin-9-yl)-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair |