BDBM50061987 2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylidenemethyl]-1,9-dihydro-purin-6-one::CHEMBL306257

SMILES: Nc1nc2n(\C=C3\CC3CO)cnc2c(=O)[nH]1

InChI Key: InChIKey=BGLCIGGDZYNYIQ-DJWKRKHSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50061987 (2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylideneme...) Show SMILES Nc1nc2n(\C=C3\CC3CO)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H11N5O2/c11-10-13-8-7(9(17)14-10)12-4-15(8)2-5-1-6(5)3-16/h2,4,6,16H,1,3H2,(H3,11,13,14,17)/b5-2-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...				J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50061987 (2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylideneme...) Show SMILES Nc1nc2n(\C=C3\CC3CO)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H11N5O2/c11-10-13-8-7(9(17)14-10)12-4-15(8)2-5-1-6(5)3-16/h2,4,6,16H,1,3H2,(H3,11,13,14,17)/b5-2-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t...				J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4
					More data for this Ligand-Target Pair