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BDBM50062064 1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-benzoyl]-1H-indole-4-carboxylic acid benzyl ester::CHEMBL427307

SMILES: CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OCc1ccccc1

InChI Key: InChIKey=CXQFJDRCEWRFQR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50062064
PNG
(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OCc1ccccc1
Show InChI InChI=1S/C34H29N5O4/c1-22-36-28-18-35-17-16-29(28)38(22)19-23-12-14-25(15-13-23)32(40)27-20-39(34(42)37(2)3)30-11-7-10-26(31(27)30)33(41)43-21-24-8-5-4-6-9-24/h4-18,20H,19,21H2,1-3H3
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Article
PubMed
0.860n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes


J Med Chem 41: 74-95 (1998)


Article DOI: 10.1021/jm970389+
BindingDB Entry DOI: 10.7270/Q2MC8Z4D
More data for this
Ligand-Target Pair