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BDBM50062271 5-(4-Bromo-phenyl)-1-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidin-2-one::CHEMBL296036

SMILES: COc1ccccc1N1CCN(CCN2C(CCC2=O)c2ccc(Br)cc2)CC1

InChI Key: InChIKey=MNZGBWMSKKNBIF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062271   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50062271
PNG
(5-(4-Bromo-phenyl)-1-{2-[4-(2-methoxy-phenyl)-pipe...)
Show SMILES COc1ccccc1N1CCN(CCN2C(CCC2=O)c2ccc(Br)cc2)CC1
Show InChI InChI=1S/C23H28BrN3O2/c1-29-22-5-3-2-4-21(22)26-15-12-25(13-16-26)14-17-27-20(10-11-23(27)28)18-6-8-19(24)9-7-18/h2-9,20H,10-17H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.09n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
In vitro binding affinity for 5-hydroxytryptamine 1A receptor in rat hippocampal membranes by [125I]-labeled agonist displacement.


J Med Chem 41: 157-66 (1998)


Article DOI: 10.1021/jm970296s
BindingDB Entry DOI: 10.7270/Q2TX3DH6
More data for this
Ligand-Target Pair