BDBM50062327 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-3-methyl-1-methylcarbamoyl-butyl)-succinamide::CHEMBL70570

SMILES: CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key: InChIKey=CJQLPOBRKZCBHK-VXGBXAGGSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50062327 ((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-3-methyl-1-m...) Show SMILES CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)CC(=O)NO Show InChI InChI=1S/C15H29N3O4/c1-9(2)6-11(8-13(19)18-22)14(20)17-12(7-10(3)4)15(21)16-5/h9-12,22H,6-8H2,1-5H3,(H,16,21)(H,17,20)(H,18,19)/t11-,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50062327 ((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-3-methyl-1-m...) Show SMILES CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)CC(=O)NO Show InChI InChI=1S/C15H29N3O4/c1-9(2)6-11(8-13(19)18-22)14(20)17-12(7-10(3)4)15(21)16-5/h9-12,22H,6-8H2,1-5H3,(H,16,21)(H,17,20)(H,18,19)/t11-,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50062327 ((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-3-methyl-1-m...) Show SMILES CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)CC(=O)NO Show InChI InChI=1S/C15H29N3O4/c1-9(2)6-11(8-13(19)18-22)14(20)17-12(7-10(3)4)15(21)16-5/h9-12,22H,6-8H2,1-5H3,(H,16,21)(H,17,20)(H,18,19)/t11-,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair