BDBM50062340 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-methylcarbamoyl-2-(1-methyl-1H-indol-3-yl)-ethyl]-succinamide::CHEMBL72678

SMILES: CNC(=O)[C@H](Cc1cn(C)c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key: InChIKey=UTMWGWRRRXPAQY-PBHICJAKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50062340 ((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-methylcarb...) Show SMILES CNC(=O)[C@H](Cc1cn(C)c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO Show InChI InChI=1S/C21H30N4O4/c1-13(2)9-14(11-19(26)24-29)20(27)23-17(21(28)22-3)10-15-12-25(4)18-8-6-5-7-16(15)18/h5-8,12-14,17,29H,9-11H2,1-4H3,(H,22,28)(H,23,27)(H,24,26)/t14-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50062340 ((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-methylcarb...) Show SMILES CNC(=O)[C@H](Cc1cn(C)c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO Show InChI InChI=1S/C21H30N4O4/c1-13(2)9-14(11-19(26)24-29)20(27)23-17(21(28)22-3)10-15-12-25(4)18-8-6-5-7-16(15)18/h5-8,12-14,17,29H,9-11H2,1-4H3,(H,22,28)(H,23,27)(H,24,26)/t14-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glycomed, Inc. Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)				J Med Chem 41: 199-223 (1998) Article DOI: 10.1021/jm970494j BindingDB Entry DOI: 10.7270/Q2Q52NRB
					More data for this Ligand-Target Pair