BDBM50062408 2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL321584

SMILES: CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(cc4)C(F)(F)F)c3c12

InChI Key: InChIKey=NRCVRALBQJXGMB-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50062408 (2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-d...) Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(cc4)C(F)(F)F)c3c12 |t:1| Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-13-12-19-18-6-4-5-7-21(18)31-24(23(19)22(15)20)16-8-10-17(11-9-16)26(27,28)29/h4-14,24,30H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062408 (2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-d...) Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(cc4)C(F)(F)F)c3c12 |t:1| Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-13-12-19-18-6-4-5-7-21(18)31-24(23(19)22(15)20)16-8-10-17(11-9-16)26(27,28)29/h4-14,24,30H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity to the human progesterone receptor(hPR)assayed in CV-1 cells in cotransfection assay.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062408 (2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-d...) Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(cc4)C(F)(F)F)c3c12 |t:1| Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-13-12-19-18-6-4-5-7-21(18)31-24(23(19)22(15)20)16-8-10-17(11-9-16)26(27,28)29/h4-14,24,30H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair