BDBM50062426 5-(4-Chloro-phenyl)-9-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL107998

SMILES: COc1ccc2OC(c3ccc(Cl)cc3)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1

InChI Key: InChIKey=QHPLLVOQIJWVSH-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50062426 (5-(4-Chloro-phenyl)-9-methoxy-2,2,4-trimethyl-2,5-...) Show SMILES COc1ccc2OC(c3ccc(Cl)cc3)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:25| Show InChI InChI=1S/C26H24ClNO2/c1-15-14-26(2,3)28-21-11-10-19-20-13-18(29-4)9-12-22(20)30-25(24(19)23(15)21)16-5-7-17(27)8-6-16/h5-14,25,28H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.				J Med Chem 41: 303-10 (1998) Article DOI: 10.1021/jm9705770 BindingDB Entry DOI: 10.7270/Q2RV0PC8
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062426 (5-(4-Chloro-phenyl)-9-methoxy-2,2,4-trimethyl-2,5-...) Show SMILES COc1ccc2OC(c3ccc(Cl)cc3)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:25| Show InChI InChI=1S/C26H24ClNO2/c1-15-14-26(2,3)28-21-11-10-19-20-13-18(29-4)9-12-22(20)30-25(24(19)23(15)21)16-5-7-17(27)8-6-16/h5-14,25,28H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells.				J Med Chem 41: 303-10 (1998) Article DOI: 10.1021/jm9705770 BindingDB Entry DOI: 10.7270/Q2RV0PC8
					More data for this Ligand-Target Pair