null

SMILES: CCCSc1nsnc1OC1CN2CCC1CC2

InChI Key: InChIKey=BFCWFQDCHYZMHW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062585 (3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CCC1CC2 |(9.78,-13.42,;9.48,-11.91,;10.62,-10.88,;10.31,-9.38,;11.46,-8.36,;12.97,-8.68,;13.74,-7.33,;12.7,-6.19,;11.32,-6.82,;9.99,-6.05,;8.64,-6.82,;8.64,-8.36,;7.31,-9.12,;6,-8.36,;6,-6.82,;7.31,-6.04,;6.56,-7.38,;8.08,-7.78,)| Show InChI InChI=1S/C12H19N3OS2/c1-2-7-17-12-11(13-18-14-12)16-10-8-15-5-3-9(10)4-6-15/h9-10H,2-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062585 (3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CCC1CC2 |(9.78,-13.42,;9.48,-11.91,;10.62,-10.88,;10.31,-9.38,;11.46,-8.36,;12.97,-8.68,;13.74,-7.33,;12.7,-6.19,;11.32,-6.82,;9.99,-6.05,;8.64,-6.82,;8.64,-8.36,;7.31,-9.12,;6,-8.36,;6,-6.82,;7.31,-6.04,;6.56,-7.38,;8.08,-7.78,)| Show InChI InChI=1S/C12H19N3OS2/c1-2-7-17-12-11(13-18-14-12)16-10-8-15-5-3-9(10)4-6-15/h9-10H,2-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50062585 (3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CCC1CC2 |(9.78,-13.42,;9.48,-11.91,;10.62,-10.88,;10.31,-9.38,;11.46,-8.36,;12.97,-8.68,;13.74,-7.33,;12.7,-6.19,;11.32,-6.82,;9.99,-6.05,;8.64,-6.82,;8.64,-8.36,;7.31,-9.12,;6,-8.36,;6,-6.82,;7.31,-6.04,;6.56,-7.38,;8.08,-7.78,)| Show InChI InChI=1S/C12H19N3OS2/c1-2-7-17-12-11(13-18-14-12)16-10-8-15-5-3-9(10)4-6-15/h9-10H,2-8H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	431	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair