BDBM50062632 (S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide::1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide(L-372,460)::CHEMBL262967

SMILES: NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C2(O)c3ccccc3-c3ccccc23)CC1

InChI Key: InChIKey=WJPYSLNVRNBWAJ-KXXGJQBSSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50062632 ((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...) Show SMILES NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C2(O)c3ccccc3-c3ccccc23)CC1 |wU:9.8,(14.19,2.05,;14.19,.5,;12.85,-.27,;11.75,-1.35,;10.61,-.46,;9.27,-1.25,;7.92,-.46,;6.6,-1.25,;6.6,-2.79,;5.26,-.46,;5.74,1.01,;4.49,1.91,;3.25,1.01,;3.73,-.46,;2.38,-1.25,;2.38,-2.8,;1.06,-.48,;1.04,-2.03,;.88,1.06,;1.9,2.2,;1.42,3.67,;-.09,3.99,;-1.11,2.84,;-.63,1.38,;-1.4,.05,;-2.9,-.27,;-3.38,-1.73,;-2.34,-2.88,;-.85,-2.56,;-.37,-1.1,;12.11,-.06,;12.85,1.27,)| Show InChI InChI=1S/C26H31N3O3/c27-18-13-11-17(12-14-18)16-28-24(30)23-10-5-15-29(23)25(31)26(32)21-8-3-1-6-19(21)20-7-2-4-9-22(20)26/h1-4,6-9,17-18,23,32H,5,10-16,27H2,(H,28,30)/t17?,18?,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Binding affinity against Thrombin.				J Med Chem 43: 305-41 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2JD4XH4
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50062632 ((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...) Show SMILES NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C2(O)c3ccccc3-c3ccccc23)CC1 |wU:9.8,(14.19,2.05,;14.19,.5,;12.85,-.27,;11.75,-1.35,;10.61,-.46,;9.27,-1.25,;7.92,-.46,;6.6,-1.25,;6.6,-2.79,;5.26,-.46,;5.74,1.01,;4.49,1.91,;3.25,1.01,;3.73,-.46,;2.38,-1.25,;2.38,-2.8,;1.06,-.48,;1.04,-2.03,;.88,1.06,;1.9,2.2,;1.42,3.67,;-.09,3.99,;-1.11,2.84,;-.63,1.38,;-1.4,.05,;-2.9,-.27,;-3.38,-1.73,;-2.34,-2.88,;-.85,-2.56,;-.37,-1.1,;12.11,-.06,;12.85,1.27,)| Show InChI InChI=1S/C26H31N3O3/c27-18-13-11-17(12-14-18)16-28-24(30)23-10-5-15-29(23)25(31)26(32)21-8-3-1-6-19(21)20-7-2-4-9-22(20)26/h1-4,6-9,17-18,23,32H,5,10-16,27H2,(H,28,30)/t17?,18?,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Binding affinity against Trypsin				J Med Chem 43: 305-41 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2JD4XH4
					More data for this Ligand-Target Pair