BDBM50062663 2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid (2,6-dichloro-pyrimidin-4-yl)-amide::CHEMBL336099

SMILES: FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)nc(Cl)n1

InChI Key: InChIKey=VJBLSDVEUIUMEE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activating transcription factor 1 (Homo sapiens (Human))	BDBM50062663 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)nc(Cl)n1 Show InChI InChI=1S/C10H3Cl3F3N5O/c11-4-1-5(20-9(13)18-4)19-7(22)3-2-17-8(12)21-6(3)10(14,15)16/h1-2H,(H,18,19,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1				J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B (NF-kB) (Homo sapiens (Human))	BDBM50062663 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)nc(Cl)n1 Show InChI InChI=1S/C10H3Cl3F3N5O/c11-4-1-5(20-9(13)18-4)19-7(22)3-2-17-8(12)21-6(3)10(14,15)16/h1-2H,(H,18,19,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor				J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ
					More data for this Ligand-Target Pair