BDBM50062797 3-{(S)-1-[2-(4-Carbamimidoyl-benzoylamino)-acetyl]-4-carboxymethyl-3-oxo-piperazin-2-yl}-propionic acid methyl ester::CHEMBL344544

SMILES: COC(=O)CC[C@@H]1N(CCN(CC(O)=O)C1=O)C(=O)CNC(=O)c1ccc(cc1)C(N)=N

InChI Key: InChIKey=CRYXEQGCGZTMIV-AWEZNQCLSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062797 (3-{(S)-1-[2-(4-Carbamimidoyl-benzoylamino)-acetyl]...) Show SMILES COC(=O)CC[C@@H]1N(CCN(CC(O)=O)C1=O)C(=O)CNC(=O)c1ccc(cc1)C(N)=N Show InChI InChI=1S/C20H25N5O7/c1-32-17(29)7-6-14-20(31)24(11-16(27)28)8-9-25(14)15(26)10-23-19(30)13-4-2-12(3-5-13)18(21)22/h2-5,14H,6-11H2,1H3,(H3,21,22)(H,23,30)(H,27,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062797 (3-{(S)-1-[2-(4-Carbamimidoyl-benzoylamino)-acetyl]...) Show SMILES COC(=O)CC[C@@H]1N(CCN(CC(O)=O)C1=O)C(=O)CNC(=O)c1ccc(cc1)C(N)=N Show InChI InChI=1S/C20H25N5O7/c1-32-17(29)7-6-14-20(31)24(11-16(27)28)8-9-25(14)15(26)10-23-19(30)13-4-2-12(3-5-13)18(21)22/h2-5,14H,6-11H2,1H3,(H3,21,22)(H,23,30)(H,27,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062797 (3-{(S)-1-[2-(4-Carbamimidoyl-benzoylamino)-acetyl]...) Show SMILES COC(=O)CC[C@@H]1N(CCN(CC(O)=O)C1=O)C(=O)CNC(=O)c1ccc(cc1)C(N)=N Show InChI InChI=1S/C20H25N5O7/c1-32-17(29)7-6-14-20(31)24(11-16(27)28)8-9-25(14)15(26)10-23-19(30)13-4-2-12(3-5-13)18(21)22/h2-5,14H,6-11H2,1H3,(H3,21,22)(H,23,30)(H,27,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitro				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair