BDBM50062808 CHEMBL147921::{(S)-4-Carboxymethyl-1-[2-(4-guanidinomethyl-benzoylamino)-acetyl]-3-oxo-piperazin-2-yl}-acetic acid

SMILES: NC(=N)NCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O

InChI Key: InChIKey=MVSMMWWPHRKZSJ-ZDUSSCGKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062808 (CHEMBL147921 | {(S)-4-Carboxymethyl-1-[2-(4-guanid...) Show SMILES NC(=N)NCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O Show InChI InChI=1S/C19H24N6O7/c20-19(21)23-8-11-1-3-12(4-2-11)17(31)22-9-14(26)25-6-5-24(10-16(29)30)18(32)13(25)7-15(27)28/h1-4,13H,5-10H2,(H,22,31)(H,27,28)(H,29,30)(H4,20,21,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062808 (CHEMBL147921 | {(S)-4-Carboxymethyl-1-[2-(4-guanid...) Show SMILES NC(=N)NCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O Show InChI InChI=1S/C19H24N6O7/c20-19(21)23-8-11-1-3-12(4-2-11)17(31)22-9-14(26)25-6-5-24(10-16(29)30)18(32)13(25)7-15(27)28/h1-4,13H,5-10H2,(H,22,31)(H,27,28)(H,29,30)(H4,20,21,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitro				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50062808 (CHEMBL147921 | {(S)-4-Carboxymethyl-1-[2-(4-guanid...) Show SMILES NC(=N)NCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O Show InChI InChI=1S/C19H24N6O7/c20-19(21)23-8-11-1-3-12(4-2-11)17(31)22-9-14(26)25-6-5-24(10-16(29)30)18(32)13(25)7-15(27)28/h1-4,13H,5-10H2,(H,22,31)(H,27,28)(H,29,30)(H4,20,21,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.				J Med Chem 41: 489-502 (1998) Article DOI: 10.1021/jm970235u BindingDB Entry DOI: 10.7270/Q2571B4W
					More data for this Ligand-Target Pair