BDBM50062816 5-Nitroso-6-(pyridin-4-ylmethoxy)-pyrimidine-2,4-diamine::CHEMBL358907

SMILES: Nc1nc(N)c(N=O)c(OCc2ccncc2)n1

InChI Key: InChIKey=BBSXXLUWISWPMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-O-methylguanine-DNA methyltransferase (Homo sapiens (Human))	BDBM50062816 (5-Nitroso-6-(pyridin-4-ylmethoxy)-pyrimidine-2,4-d...) Show SMILES Nc1nc(N)c(N=O)c(OCc2ccncc2)n1 Show InChI InChI=1S/C10H10N6O2/c11-8-7(16-17)9(15-10(12)14-8)18-5-6-1-3-13-4-2-6/h1-4H,5H2,(H4,11,12,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
					More data for this Ligand-Target Pair