BDBM50063006 CHEMBL3398095
SMILES: Cc1cc(C)cc(Cn2c(=O)ccn(CC(=O)Nc3ccccc3Cl)c2=O)c1
InChI Key: InChIKey=KHFVLDFREXVABG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50063006 (CHEMBL3398095) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Volgograd State Medical University Curated by ChEMBL | Assay Description Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and... | Bioorg Med Chem 23: 1069-81 (2015) Article DOI: 10.1016/j.bmc.2015.01.002 BindingDB Entry DOI: 10.7270/Q2RR20XW | |||||||||||
More data for this Ligand-Target Pair |