BDBM50063008 CHEMBL3398097

SMILES: Cc1cc(C)cc(Cn2c(=O)ccn(CC(=O)Nc3cccc(Cl)c3)c2=O)c1

InChI Key: InChIKey=NHEGJNVSNJBFHC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50063008 (CHEMBL3398097) Show SMILES Cc1cc(C)cc(Cn2c(=O)ccn(CC(=O)Nc3cccc(Cl)c3)c2=O)c1 Show InChI InChI=1S/C21H20ClN3O3/c1-14-8-15(2)10-16(9-14)12-25-20(27)6-7-24(21(25)28)13-19(26)23-18-5-3-4-17(22)11-18/h3-11H,12-13H2,1-2H3,(H,23,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
Volgograd State Medical University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...				Bioorg Med Chem 23: 1069-81 (2015) Article DOI: 10.1016/j.bmc.2015.01.002 BindingDB Entry DOI: 10.7270/Q2RR20XW
					More data for this Ligand-Target Pair