BDBM50063069 CHEMBL3398409

SMILES: Cc1cc(C(=O)NC(CC(O)=O)c2ccc(Cl)cc2)c(C)o1

InChI Key: InChIKey=QMBBVWSDUBOAJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM50063069 (CHEMBL3398409) Show SMILES Cc1cc(C(=O)NC(CC(O)=O)c2ccc(Cl)cc2)c(C)o1 Show InChI InChI=1S/C16H16ClNO4/c1-9-7-13(10(2)22-9)16(21)18-14(8-15(19)20)11-3-5-12(17)6-4-11/h3-7,14H,8H2,1-2H3,(H,18,21)(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins using ATRA and NADPH by HPLC method				Bioorg Med Chem 23: 1356-65 (2015) Article DOI: 10.1016/j.bmc.2014.11.036 BindingDB Entry DOI: 10.7270/Q2416ZQG
					More data for this Ligand-Target Pair