BindingDB PrimarySearch

BDBM50063300 (L-N6-1-iminoethyl)lysine::(S)-6-Acetimidoylamino-2-amino-hexanoic acid::6-Acetimidoylamino-2-amino-hexanoic acid::CHEMBL1744034::CHEMBL7889::L-N6-(1-iminoethyl)lysine::N~6~-[(1Z)-ethanimidoyl]-L-lysine::l-NIL

SMILES: CC(N)=NCCCC[C@H](N)C(O)=O

InChI Key: InChIKey=ONYFNWIHJBLQKE-ZETCQYMHSA-N

Data: 1 KI 37 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50063300
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University at Buffalo Curated by ChEMBL					Assay Description The compound was tested for competitive antagonist of Nitric oxide synthase				Bioorg Med Chem Lett 10: 1077-80 (2000) BindingDB Entry DOI: 10.7270/Q2959GSN
University at Buffalo Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.70E+8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory concentration against nitric oxide synthesis in intact DLD-1 cells				Bioorg Med Chem Lett 11: 1023-6 (2001) BindingDB Entry DOI: 10.7270/Q2K073JZ
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Rahway Curated by ChEMBL					Assay Description Inhibitory activity against neuronal nitric oxide synthase				Bioorg Med Chem Lett 10: 1975-8 (2001) BindingDB Entry DOI: 10.7270/Q2319V30
Merck Research Laboratories Rahway Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cells				Bioorg Med Chem Lett 11: 1023-6 (2001) BindingDB Entry DOI: 10.7270/Q2K073JZ
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Compound was evaluated for the Inhibition of Neuronal nitric oxide synthase				J Med Chem 41: 775-7 (1998) Article DOI: 10.1021/jm9706675 BindingDB Entry DOI: 10.7270/Q2VQ31TX
Searle Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Compound was evaluated for the Inhibition of endothelial isoform of Endothelial nitric oxide synthase (eNOS)enzyme				J Med Chem 41: 775-7 (1998) Article DOI: 10.1021/jm9706675 BindingDB Entry DOI: 10.7270/Q2VQ31TX
Searle Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Compound was evaluated for the Inhibition of induced isoform of Inducible nitric oxide synthase				J Med Chem 41: 775-7 (1998) Article DOI: 10.1021/jm9706675 BindingDB Entry DOI: 10.7270/Q2VQ31TX
Searle Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric-oxide synthase, brain (Rattus norvegicus (rat))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellum				Bioorg Med Chem Lett 11: 1023-6 (2001) BindingDB Entry DOI: 10.7270/Q2K073JZ
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cells				Bioorg Med Chem Lett 11: 1023-6 (2001) BindingDB Entry DOI: 10.7270/Q2K073JZ
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description In vitro inhibition of human Inducible nitric oxide synthase.				J Med Chem 47: 3320-3 (2004) Article DOI: 10.1021/jm031035n BindingDB Entry DOI: 10.7270/Q25M656D
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description In vitro inhibition of human endothelial nitric oxide synthase.				J Med Chem 47: 3320-3 (2004) Article DOI: 10.1021/jm031035n BindingDB Entry DOI: 10.7270/Q25M656D
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description In vitro inhibition of human neuronal nitric oxide synthase.				J Med Chem 47: 3320-3 (2004) Article DOI: 10.1021/jm031035n BindingDB Entry DOI: 10.7270/Q25M656D
AstraZeneca R&D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Rattus norvegicus)	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Tested for inhibition of rat brain inducible nitric oxide synthase				J Med Chem 37: 3886-8 (1994) BindingDB Entry DOI: 10.7270/Q29P328V
G. D. Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Tested for inhibition of mouse inducible nitric oxide synthase				J Med Chem 37: 3886-8 (1994) BindingDB Entry DOI: 10.7270/Q29P328V
G. D. Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human Neuronal nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
G. D. Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human Endothelial nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
G. D. Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human inducible nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
G. D. Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description The concentration required for inhibition of Human endothelial nitric oxide synthase (eNOS) isoform				J Med Chem 45: 1686-9 (2002) BindingDB Entry DOI: 10.7270/Q2445N74
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description The concentration required for inhibition of Human inducible nitric oxide synthase (iNOS) isoform				J Med Chem 45: 1686-9 (2002) BindingDB Entry DOI: 10.7270/Q2445N74
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description The concentration required for inhibition of Human Neuronal nitric oxide synthase (nNOS)				J Med Chem 45: 1686-9 (2002) BindingDB Entry DOI: 10.7270/Q2445N74
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibitory activity against Neuronal nitric oxide synthase				Bioorg Med Chem Lett 14: 4539-44 (2004) Article DOI: 10.1016/j.bmcl.2004.06.033 BindingDB Entry DOI: 10.7270/Q218377V
Merck Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibitory activity against Inducible nitric oxide synthase				Bioorg Med Chem Lett 14: 4539-44 (2004) Article DOI: 10.1016/j.bmcl.2004.06.033 BindingDB Entry DOI: 10.7270/Q218377V
Merck Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibitory activity against Endothelial nitric oxide synthase				Bioorg Med Chem Lett 14: 4539-44 (2004) Article DOI: 10.1016/j.bmcl.2004.06.033 BindingDB Entry DOI: 10.7270/Q218377V
Merck Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition concentration against Neuronal nitric oxide synthase (nNOS) at 10 uM concentration				J Med Chem 47: 900-6 (2004) Article DOI: 10.1021/jm030348f BindingDB Entry DOI: 10.7270/Q23B60WX
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition concentration against Endothelial nitric oxide synthase (eNOS) at 10 uM concentration				J Med Chem 47: 900-6 (2004) Article DOI: 10.1021/jm030348f BindingDB Entry DOI: 10.7270/Q23B60WX
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description InInhibition concentration against Inducible nitric oxide synthase (iNOS) at 10 uM concentration				J Med Chem 47: 900-6 (2004) Article DOI: 10.1021/jm030348f BindingDB Entry DOI: 10.7270/Q23B60WX
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R& D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against human endothelial nitiric oxide synthase				J Med Chem 46: 913-6 (2003) Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M
AstraZeneca R& D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R& D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity of compound against human inducible nitiric oxide synthase				J Med Chem 46: 913-6 (2003) Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M
AstraZeneca R& D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R& D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against human neuronal nitiric oxide synthase				J Med Chem 46: 913-6 (2003) Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M
AstraZeneca R& D Charnwood Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Inhibition of human nNOS expressed in insect SF9 cells after 1 hr				Bioorg Med Chem Lett 18: 336-43 (2008) Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q
Adolor Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Inhibition of cytokine-induced iNOS activity in human DLD1 cells after 24 hrs				Bioorg Med Chem Lett 18: 336-43 (2008) Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q
Adolor Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in human DLD1 cells after 1 hr				Bioorg Med Chem Lett 18: 336-43 (2008) Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q
Adolor Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Inhibition of human eNOS expressed in insect SF9 cells after 1 hr				Bioorg Med Chem Lett 18: 336-43 (2008) Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q
Adolor Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting				Bioorg Med Chem Lett 21: 4228-32 (2011) Article DOI: 10.1016/j.bmcl.2011.05.073 BindingDB Entry DOI: 10.7270/Q2H996GJ
Nycomed GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting				Bioorg Med Chem Lett 21: 4228-32 (2011) Article DOI: 10.1016/j.bmcl.2011.05.073 BindingDB Entry DOI: 10.7270/Q2H996GJ
Nycomed GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation counting				Bioorg Med Chem Lett 21: 4228-32 (2011) Article DOI: 10.1016/j.bmcl.2011.05.073 BindingDB Entry DOI: 10.7270/Q2H996GJ
Nycomed GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Rahway Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 10: 1975-8 (2001) BindingDB Entry DOI: 10.7270/Q2319V30
Merck Research Laboratories Rahway Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50063300 ((L-N6-1-iminoethyl)lysine \| (S)-6-Acetimidoylamino...) Show SMILES CC(N)=NCCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Rahway Curated by ChEMBL					Assay Description Inhibitory activity against inducible nitric oxide synthase (iNOS)				Bioorg Med Chem Lett 10: 1975-8 (2001) BindingDB Entry DOI: 10.7270/Q2319V30
Merck Research Laboratories Rahway Curated by ChEMBL					More data for this Ligand-Target Pair