BDBM50063517 CHEMBL3398524

SMILES: Cn1c(-c2cccs2)c(Cl)c2cc(C#N)c(cc12)C#N

InChI Key: InChIKey=AWFDTQKILWJQCK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50063517 (CHEMBL3398524) Show SMILES Cn1c(-c2cccs2)c(Cl)c2cc(C#N)c(cc12)C#N Show InChI InChI=1S/C15H8ClN3S/c1-19-12-6-10(8-18)9(7-17)5-11(12)14(16)15(19)13-3-2-4-20-13/h2-6H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Yaroslavl State Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A assessed as kynuramine oxidation to 4-hydroxyquinoline formation by spectrofluorometric analysis				Bioorg Med Chem Lett 25: 1206-11 (2015) Article DOI: 10.1016/j.bmcl.2015.01.061 BindingDB Entry DOI: 10.7270/Q2M32XDJ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50063517 (CHEMBL3398524) Show SMILES Cn1c(-c2cccs2)c(Cl)c2cc(C#N)c(cc12)C#N Show InChI InChI=1S/C15H8ClN3S/c1-19-12-6-10(8-18)9(7-17)5-11(12)14(16)15(19)13-3-2-4-20-13/h2-6H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yaroslavl State Technical University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B assessed as kynuramine oxidation to 4-hydroxyquinoline formation by spectrofluorometric analysis				Bioorg Med Chem Lett 25: 1206-11 (2015) Article DOI: 10.1016/j.bmcl.2015.01.061 BindingDB Entry DOI: 10.7270/Q2M32XDJ
					More data for this Ligand-Target Pair