BDBM50063738 2-(2-Trifluoromethoxy-phenylamino)-benzo[d][1,3]oxazin-4-one::CHEMBL10254
SMILES: FC(F)(F)Oc1ccccc1Nc1nc2ccccc2c(=O)o1
InChI Key: InChIKey=QMPGYVFSCPYRTB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Complement C1r subcomponent (Homo sapiens (Human)) | BDBM50063738 (2-(2-Trifluoromethoxy-phenylamino)-benzo[d][1,3]ox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrate | J Med Chem 41: 1060-7 (1998) Article DOI: 10.1021/jm970394d BindingDB Entry DOI: 10.7270/Q2PZ57ZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Complement C1r subcomponent (Homo sapiens (Human)) | BDBM50063738 (2-(2-Trifluoromethoxy-phenylamino)-benzo[d][1,3]ox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >6.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description 50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrate | J Med Chem 41: 1060-7 (1998) Article DOI: 10.1021/jm970394d BindingDB Entry DOI: 10.7270/Q2PZ57ZT | |||||||||||
More data for this Ligand-Target Pair |