BDBM50063874 CHEMBL3400911
SMILES: CC(C)(C)c1ccc(COc2ccc3[nH]c4C(CC(O)=O)NCCc4c3c2)cc1
InChI Key: InChIKey=FLDKNXKMJXYYOQ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50063874 (CHEMBL3400911) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay | Bioorg Med Chem Lett 25: 659-63 (2015) Article DOI: 10.1016/j.bmcl.2014.11.089 BindingDB Entry DOI: 10.7270/Q25T3N5P | |||||||||||
More data for this Ligand-Target Pair |