BDBM50064072 4-Oxo-2-[3-(quinolin-2-ylmethoxy)-phenyl]-4H-chromene-8-carboxylic acid::4-oxo-2-(3-(quinolin-2-ylmethoxy)phenyl)-4H-chromene-8-carboxylic acid::CHEMBL33871

SMILES: OC(=O)c1cccc2c1oc(cc2=O)-c1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=KHHUBZJYSQUQNW-UHFFFAOYSA-N

Data: 2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50064072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50064072 (4-Oxo-2-[3-(quinolin-2-ylmethoxy)-phenyl]-4H-chrom...) Show SMILES OC(=O)c1cccc2c1oc(cc2=O)-c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H17NO5/c28-23-14-24(32-25-20(23)8-4-9-21(25)26(29)30)17-6-3-7-19(13-17)31-15-18-12-11-16-5-1-2-10-22(16)27-18/h1-14H,15H2,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]-LTD4.				J Med Chem 41: 1428-38 (1998) Article DOI: 10.1021/jm970179x BindingDB Entry DOI: 10.7270/Q21835MZ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50064072 (4-Oxo-2-[3-(quinolin-2-ylmethoxy)-phenyl]-4H-chrom...) Show SMILES OC(=O)c1cccc2c1oc(cc2=O)-c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H17NO5/c28-23-14-24(32-25-20(23)8-4-9-21(25)26(29)30)17-6-3-7-19(13-17)31-15-18-12-11-16-5-1-2-10-22(16)27-18/h1-14H,15H2,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50064072 (4-Oxo-2-[3-(quinolin-2-ylmethoxy)-phenyl]-4H-chrom...) Show SMILES OC(=O)c1cccc2c1oc(cc2=O)-c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H17NO5/c28-23-14-24(32-25-20(23)8-4-9-21(25)26(29)30)17-6-3-7-19(13-17)31-15-18-12-11-16-5-1-2-10-22(16)27-18/h1-14H,15H2,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligand				J Med Chem 41: 1439-45 (1998) Article DOI: 10.1021/jm970180w BindingDB Entry DOI: 10.7270/Q2WH2P4P
					More data for this Ligand-Target Pair