BDBM50064112 (S)-5-(2-Fluoro-phenyl)-2-[(S)-5-(2-fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-pent-4-ynoic acid::CHEMBL39777

SMILES: OC(=O)[C@H](CC#Cc1ccccc1F)NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O

InChI Key: InChIKey=LEUUZEFIWDNUGB-SFTDATJTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50064112 ((S)-5-(2-Fluoro-phenyl)-2-[(S)-5-(2-fluoro-phenyl)...) Show SMILES OC(=O)[C@H](CC#Cc1ccccc1F)NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O Show InChI InChI=1S/C23H21F2N2O6P/c24-18-11-3-1-7-16(18)9-5-13-20(26-15-34(31,32)33)22(28)27-21(23(29)30)14-6-10-17-8-2-4-12-19(17)25/h1-4,7-8,11-12,20-21,26H,13-15H2,(H,27,28)(H,29,30)(H2,31,32,33)/t20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibitory activity against neutral endopeptidase (NEP).				J Med Chem 41: 1513-23 (1998) Article DOI: 10.1021/jm970787c BindingDB Entry DOI: 10.7270/Q2PV6M1M
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50064112 ((S)-5-(2-Fluoro-phenyl)-2-[(S)-5-(2-fluoro-phenyl)...) Show SMILES OC(=O)[C@H](CC#Cc1ccccc1F)NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O Show InChI InChI=1S/C23H21F2N2O6P/c24-18-11-3-1-7-16(18)9-5-13-20(26-15-34(31,32)33)22(28)27-21(23(29)30)14-6-10-17-8-2-4-12-19(17)25/h1-4,7-8,11-12,20-21,26H,13-15H2,(H,27,28)(H,29,30)(H2,31,32,33)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).				J Med Chem 41: 1513-23 (1998) Article DOI: 10.1021/jm970787c BindingDB Entry DOI: 10.7270/Q2PV6M1M
					More data for this Ligand-Target Pair