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SMILES: CC(C)COc1nc2sc(C)c(C)c2c(=O)o1

InChI Key: InChIKey=JGEZDBLNWKUNQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064309   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50064309
PNG
(2-Isobutoxy-5,6-dimethyl-thieno[2,3-d][1,3]oxazin-...)
Show SMILES CC(C)COc1nc2sc(C)c(C)c2c(=O)o1
Show InChI InChI=1S/C12H15NO3S/c1-6(2)5-15-12-13-10-9(11(14)16-12)7(3)8(4)17-10/h6H,5H2,1-4H3
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Similars
Article
PubMed
 133n/an/an/an/a 0.0000292 219n/an/a



University of Leipzig

Curated by ChEMBL


Assay Description
Steady state inhibition constant for Human Leukocyte Elastase inhibition

J Med Chem 41: 1729-40 (1998)


Article DOI: 10.1021/jm9708341
BindingDB Entry DOI: 10.7270/Q2QV3KNF
More data for this
Ligand-Target Pair