BDBM50064559 CHEMBL61470::Piperidin-1-yl-{3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone

SMILES: FC(F)(F)c1cccc(c1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1

InChI Key: InChIKey=DHBAVPRIEVIAEK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50064559 (CHEMBL61470 | Piperidin-1-yl-{3-[4-(3-trifluoromet...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C24H28F3N3O/c25-24(26,27)21-8-5-9-22(17-21)29-14-12-28(13-15-29)18-19-6-4-7-20(16-19)23(31)30-10-2-1-3-11-30/h4-9,16-17H,1-3,10-15,18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortex				J Med Chem 41: 1997-2009 (1998) Article DOI: 10.1021/jm970164z BindingDB Entry DOI: 10.7270/Q2KK9CG0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50064559 (CHEMBL61470 | Piperidin-1-yl-{3-[4-(3-trifluoromet...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C24H28F3N3O/c25-24(26,27)21-8-5-9-22(17-21)29-14-12-28(13-15-29)18-19-6-4-7-20(16-19)23(31)30-10-2-1-3-11-30/h4-9,16-17H,1-3,10-15,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	682	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 from rat striatum				J Med Chem 41: 1997-2009 (1998) Article DOI: 10.1021/jm970164z BindingDB Entry DOI: 10.7270/Q2KK9CG0
					More data for this Ligand-Target Pair