BDBM50064936 CHEMBL63360::{1-[(E)-5-(4-Carbamimidoyl-phenyl)-2,2-dimethyl-5-oxo-pent-3-enoyl]-piperidin-4-yl}-acetic acid
SMILES: CC(C)(\C=C\C(=O)c1ccc(cc1)C(N)=N)C(=O)N1CCC(CC(O)=O)CC1
InChI Key: InChIKey=DNIHCIKOFWOAIQ-JXMROGBWSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50064936 (CHEMBL63360 | {1-[(E)-5-(4-Carbamimidoyl-phenyl)-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against platelet aggregation | Bioorg Med Chem Lett 10: 859-63 (2000) BindingDB Entry DOI: 10.7270/Q2W95BFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50064936 (CHEMBL63360 | {1-[(E)-5-(4-Carbamimidoyl-phenyl)-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Steel Corporation Curated by ChEMBL | Assay Description Binding affinity to human fibrinogen receptor | J Med Chem 41: 2345-60 (1998) Article DOI: 10.1021/jm980126v BindingDB Entry DOI: 10.7270/Q2WD3ZPH | |||||||||||
More data for this Ligand-Target Pair |