BDBM50065040 CHEMBL3402682

SMILES: Cl.CN(C)[C@H]1C[C@H](c2cccc(c2)-c2ccccc2)c2ccccc2C1

InChI Key: InChIKey=HOAKRAGPAPUBMD-NOURSWRJSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50065040 (CHEMBL3402682) Show SMILES Cl.CN(C)[C@H]1C[C@H](c2cccc(c2)-c2ccccc2)c2ccccc2C1 |r| Show InChI InChI=1S/C24H25N.ClH/c1-25(2)22-16-21-11-6-7-14-23(21)24(17-22)20-13-8-12-19(15-20)18-9-4-3-5-10-18;/h3-15,22,24H,16-17H2,1-2H3;1H/t22-,24-;/m1./s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [3H]Mesulergine from human 5-HT2C-INI receptor expressed in HEK293 cells by scintillation counting analysis				Bioorg Med Chem 23: 1588-600 (2015) Article DOI: 10.1016/j.bmc.2015.01.060 BindingDB Entry DOI: 10.7270/Q2TF0010
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50065040 (CHEMBL3402682) Show SMILES Cl.CN(C)[C@H]1C[C@H](c2cccc(c2)-c2ccccc2)c2ccccc2C1 |r| Show InChI InChI=1S/C24H25N.ClH/c1-25(2)22-16-21-11-6-7-14-23(21)24(17-22)20-13-8-12-19(15-20)18-9-4-3-5-10-18;/h3-15,22,24H,16-17H2,1-2H3;1H/t22-,24-;/m1./s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in HEK293 cells by scintillation counting analysis				Bioorg Med Chem 23: 1588-600 (2015) Article DOI: 10.1016/j.bmc.2015.01.060 BindingDB Entry DOI: 10.7270/Q2TF0010
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50065040 (CHEMBL3402682) Show SMILES Cl.CN(C)[C@H]1C[C@H](c2cccc(c2)-c2ccccc2)c2ccccc2C1 |r| Show InChI InChI=1S/C24H25N.ClH/c1-25(2)22-16-21-11-6-7-14-23(21)24(17-22)20-13-8-12-19(15-20)18-9-4-3-5-10-18;/h3-15,22,24H,16-17H2,1-2H3;1H/t22-,24-;/m1./s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293 cells by scintillation counting analysis				Bioorg Med Chem 23: 1588-600 (2015) Article DOI: 10.1016/j.bmc.2015.01.060 BindingDB Entry DOI: 10.7270/Q2TF0010
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50065040 (CHEMBL3402682) Show SMILES Cl.CN(C)[C@H]1C[C@H](c2cccc(c2)-c2ccccc2)c2ccccc2C1 |r| Show InChI InChI=1S/C24H25N.ClH/c1-25(2)22-16-21-11-6-7-14-23(21)24(17-22)20-13-8-12-19(15-20)18-9-4-3-5-10-18;/h3-15,22,24H,16-17H2,1-2H3;1H/t22-,24-;/m1./s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor expressed in HEK293 cells				Bioorg Med Chem 23: 1588-600 (2015) Article DOI: 10.1016/j.bmc.2015.01.060 BindingDB Entry DOI: 10.7270/Q2TF0010
					More data for this Ligand-Target Pair