BDBM50065113 CHEMBL310581::N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-phenyl]-4-chloro-2-methoxy-benzamide

SMILES: COc1cc(Cl)ccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12

InChI Key: InChIKey=KYYYGMCGDBPAIF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AVPR1A (RAT)	BDBM50065113 (CHEMBL310581 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...) Show SMILES COc1cc(Cl)ccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12 Show InChI InChI=1S/C27H22ClN3O3/c1-34-25-15-20(28)10-13-23(25)26(32)29-21-11-8-18(9-12-21)27(33)31-17-22-6-4-14-30(22)16-19-5-2-3-7-24(19)31/h2-15H,16-17H2,1H3,(H,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Displacement of (Phe-3,4,5-H) Vasopressin from V1a recptor from rat liver membranes.				J Med Chem 41: 2442-4 (1998) Article DOI: 10.1021/jm980179c BindingDB Entry DOI: 10.7270/Q2CC0ZT5
					More data for this Ligand-Target Pair
Vasopressin V2 Receptor (Rattus norvegicus (Rat))	BDBM50065113 (CHEMBL310581 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...) Show SMILES COc1cc(Cl)ccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12 Show InChI InChI=1S/C27H22ClN3O3/c1-34-25-15-20(28)10-13-23(25)26(32)29-21-11-8-18(9-12-21)27(33)31-17-22-6-4-14-30(22)16-19-5-2-3-7-24(19)31/h2-15H,16-17H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from vasopressin V2 receptor of rat kidney medulla.				J Med Chem 41: 2442-4 (1998) Article DOI: 10.1021/jm980179c BindingDB Entry DOI: 10.7270/Q2CC0ZT5
					More data for this Ligand-Target Pair