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BDBM50065135 4-Iodo-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide::CHEMBL79840

SMILES: Ic1ccc(cc1)S(=O)(=O)NCCN1CCCC1

InChI Key: InChIKey=BHBINLGLGSKTJE-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065135   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50065135
PNG
(4-Iodo-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonam...)
Show SMILES Ic1ccc(cc1)S(=O)(=O)NCCN1CCCC1
Show InChI InChI=1S/C12H17IN2O2S/c13-11-3-5-12(6-4-11)18(16,17)14-7-10-15-8-1-2-9-15/h3-6,14H,1-2,7-10H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.46n/an/an/an/an/an/an/an/a



The George Washington University Medical Center

Curated by ChEMBL


Assay Description
Inhibition Constant for 4-[125I]-IPBS binding to sigma 1 receptor in guinea pig brain membranes


J Med Chem 41: 2445-50 (1998)


Article DOI: 10.1021/jm9800447
BindingDB Entry DOI: 10.7270/Q27P8XHM
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50065135
PNG
(4-Iodo-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonam...)
Show SMILES Ic1ccc(cc1)S(=O)(=O)NCCN1CCCC1
Show InChI InChI=1S/C12H17IN2O2S/c13-11-3-5-12(6-4-11)18(16,17)14-7-10-15-8-1-2-9-15/h3-6,14H,1-2,7-10H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
4.30n/an/an/an/an/an/an/an/a



The George Washington University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes


J Med Chem 41: 2445-50 (1998)


Article DOI: 10.1021/jm9800447
BindingDB Entry DOI: 10.7270/Q27P8XHM
More data for this
Ligand-Target Pair