null

SMILES: Fc1ccccc1C#CCO\N=C1/CN2CCC1C2

InChI Key: InChIKey=OESVJCHGVUTKBW-BMRADRMJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50065208 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-fluoro-ph...) Show SMILES Fc1ccccc1C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C15H15FN2O/c16-14-6-2-1-4-12(14)5-3-9-19-17-15-11-18-8-7-13(15)10-18/h1-2,4,6,13H,7-11H2/b17-15+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of [3H]-QNB to CHO cells expressing human Muscarinic acetylcholine receptor M1				J Med Chem 41: 2524-36 (1998) Article DOI: 10.1021/jm960683m BindingDB Entry DOI: 10.7270/Q2VD6XKK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50065208 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-fluoro-ph...) Show SMILES Fc1ccccc1C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C15H15FN2O/c16-14-6-2-1-4-12(14)5-3-9-19-17-15-11-18-8-7-13(15)10-18/h1-2,4,6,13H,7-11H2/b17-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity towards muscarinic receptor using [3H]cis-methyldioxolane (CMD) to label agonist sites in membrane preparations from rat neocortex				Citation and Details BindingDB Entry DOI: 10.7270/Q2736T2X
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50065208 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-fluoro-ph...) Show SMILES Fc1ccccc1C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C15H15FN2O/c16-14-6-2-1-4-12(14)5-3-9-19-17-15-11-18-8-7-13(15)10-18/h1-2,4,6,13H,7-11H2/b17-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	4.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity towards muscarinic receptor using [3H]quinuclidinyl benzilate (QNB) to label antagonist sites in membrane preparations from rat neoc...				Citation and Details BindingDB Entry DOI: 10.7270/Q2736T2X
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50065208 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-fluoro-ph...) Show SMILES Fc1ccccc1C#CCO\N=C1/CN2CCC1C2 Show InChI InChI=1S/C15H15FN2O/c16-14-6-2-1-4-12(14)5-3-9-19-17-15-11-18-8-7-13(15)10-18/h1-2,4,6,13H,7-11H2/b17-15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity of [3H]-QNB to CHO cells expressing human Muscarinic acetylcholine receptor M2				J Med Chem 41: 2524-36 (1998) Article DOI: 10.1021/jm960683m BindingDB Entry DOI: 10.7270/Q2VD6XKK
					More data for this Ligand-Target Pair