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BDBM50065246 CHEMBL3403828

SMILES: C[C@H](CO)Nc1cc(nc(SCc2ccccc2)n1)C(O)=O

InChI Key: InChIKey=WFLYFJAGCGTNQW-UEQNJFAPNA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065246   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM50065246
PNG
(CHEMBL3403828)
Show SMILES C[C@H](CO)Nc1cc(nc(SCc2ccccc2)n1)C(O)=O |r|
Show InChI InChI=1/C15H17N3O3S/c1-10(8-19)16-13-7-12(14(20)21)17-15(18-13)22-9-11-5-3-2-4-6-11/h2-7,10,19H,8-9H2,1H3,(H,20,21)(H,16,17,18)/t10-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 398n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [125I]IL-8 from human recombinant CXCR2 receptor expressed in HEK293 cells by scintillation counting analysis


Bioorg Med Chem Lett 25: 1616-20 (2015)


Article DOI: 10.1016/j.bmcl.2015.01.067
BindingDB Entry DOI: 10.7270/Q2F47QT4
More data for this
Ligand-Target Pair