BDBM50065260 1-((3R,4S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one::CHEMBL87519
SMILES: OCC1OC([C@H](O)[C@@H]1O)n1cccnc1=O
InChI Key: InChIKey=RPQZTTQVRYEKCR-MIDKJMSJSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytidine deaminase (CDA) (Homo sapiens (Human)) | BDBM50065260 (1-((3R,4S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Apparent Ki (binding affinity) was calculated for the compound against cytidine deaminase. | J Med Chem 41: 2572-8 (1998) Article DOI: 10.1021/jm980111x BindingDB Entry DOI: 10.7270/Q2KW5F6T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytidine deaminase (CDA) (Homo sapiens (Human)) | BDBM50065260 (1-((3R,4S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against cytidine deaminase. | J Med Chem 41: 2572-8 (1998) Article DOI: 10.1021/jm980111x BindingDB Entry DOI: 10.7270/Q2KW5F6T | |||||||||||
More data for this Ligand-Target Pair |