BDBM50065266 CHEMBL3403839

SMILES: C[C@H](CO)Nc1cc(NS(=O)(=O)Cc2ccccc2)nc(SCc2ccccc2)n1

InChI Key: InChIKey=RWKCBMYEKIDCDN-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50065266 (CHEMBL3403839) Show SMILES C[C@H](CO)Nc1cc(NS(=O)(=O)Cc2ccccc2)nc(SCc2ccccc2)n1 |r| Show InChI InChI=1S/C21H24N4O3S2/c1-16(13-26)22-19-12-20(25-30(27,28)15-18-10-6-3-7-11-18)24-21(23-19)29-14-17-8-4-2-5-9-17/h2-12,16,26H,13-15H2,1H3,(H2,22,23,24,25)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]IL-8 from human recombinant CXCR2 receptor expressed in HEK293 cells by scintillation counting analysis				Bioorg Med Chem Lett 25: 1616-20 (2015) Article DOI: 10.1016/j.bmcl.2015.01.067 BindingDB Entry DOI: 10.7270/Q2F47QT4
					More data for this Ligand-Target Pair