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BDBM50065323 CHEMBL3403847

SMILES: C[C@H](CO)Nc1cc(NS(=O)(=O)c2cn(C)cn2)nc(SCc2cccc(Cl)c2F)n1

InChI Key: InChIKey=NRRSGTIRDLBPLB-LDGXTIHJNA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065323   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50065323
PNG
(CHEMBL3403847)
Show SMILES C[C@H](CO)Nc1cc(NS(=O)(=O)c2cn(C)cn2)nc(SCc2cccc(Cl)c2F)n1
Show InChI InChI=1/C18H20ClFN6O3S2/c1-11(8-27)22-14-6-15(25-31(28,29)16-7-26(2)10-21-16)24-18(23-14)30-9-12-4-3-5-13(19)17(12)20/h3-7,10-11,27H,8-9H2,1-2H3,(H2,22,23,24,25)/t11-/s2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [125I]IL-8 from human recombinant CXCR2 receptor expressed in HEK293 cells by scintillation counting analysis


Bioorg Med Chem Lett 25: 1616-20 (2015)

More data for this
Ligand-Target Pair