BDBM50065485 CHEMBL3402760

SMILES: CN(C)CCCOc1cnc(nc1)-c1cccc(Cn2nc(ccc2=O)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=PPCTYYSLBWDGHQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50065485 (CHEMBL3402760) Show SMILES CN(C)CCCOc1cnc(nc1)-c1cccc(Cn2nc(ccc2=O)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C27H26N6O2/c1-32(2)12-5-13-35-24-17-29-27(30-18-24)23-9-4-7-21(15-23)19-33-26(34)11-10-25(31-33)22-8-3-6-20(14-22)16-28/h3-4,6-11,14-15,17-18H,5,12-13,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Research& Development Curated by ChEMBL					Assay Description Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assay				Bioorg Med Chem Lett 25: 1597-602 (2015) Article DOI: 10.1016/j.bmcl.2015.02.002 BindingDB Entry DOI: 10.7270/Q2HX1FBT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50065485 (CHEMBL3402760) Show SMILES CN(C)CCCOc1cnc(nc1)-c1cccc(Cn2nc(ccc2=O)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C27H26N6O2/c1-32(2)12-5-13-35-24-17-29-27(30-18-24)23-9-4-7-21(15-23)19-33-26(34)11-10-25(31-33)22-8-3-6-20(14-22)16-28/h3-4,6-11,14-15,17-18H,5,12-13,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Research& Development Curated by ChEMBL					Assay Description Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assay				Bioorg Med Chem Lett 25: 1597-602 (2015) Article DOI: 10.1016/j.bmcl.2015.02.002 BindingDB Entry DOI: 10.7270/Q2HX1FBT
					More data for this Ligand-Target Pair