BDBM50065494 CHEMBL3402764

SMILES: CN(C)CCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-c2ccc(F)cc2)c1

InChI Key: InChIKey=KCAPWBJRKSKHSZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50065494 (CHEMBL3402764) Show SMILES CN(C)CCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-c2ccc(F)cc2)c1 Show InChI InChI=1S/C23H25FN4O3/c1-27(2)13-4-14-31-23(30)25-20-6-3-5-17(15-20)16-28-22(29)12-11-21(26-28)18-7-9-19(24)10-8-18/h3,5-12,15H,4,13-14,16H2,1-2H3,(H,25,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Research& Development Curated by ChEMBL					Assay Description Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assay				Bioorg Med Chem Lett 25: 1597-602 (2015) Article DOI: 10.1016/j.bmcl.2015.02.002 BindingDB Entry DOI: 10.7270/Q2HX1FBT
					More data for this Ligand-Target Pair