BDBM50065495 CHEMBL3402763

SMILES: CCN(CC)CCCOC(=O)Nc1cccc(CN2N=C(CSC2=O)c2ccc(Cl)cc2)c1

InChI Key: InChIKey=XSINRHAIBWWSLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50065495 (CHEMBL3402763) Show SMILES CCN(CC)CCCOC(=O)Nc1cccc(CN2N=C(CSC2=O)c2ccc(Cl)cc2)c1 |c:19| Show InChI InChI=1S/C24H29ClN4O3S/c1-3-28(4-2)13-6-14-32-23(30)26-21-8-5-7-18(15-21)16-29-24(31)33-17-22(27-29)19-9-11-20(25)12-10-19/h5,7-12,15H,3-4,6,13-14,16-17H2,1-2H3,(H,26,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Research& Development Curated by ChEMBL					Assay Description Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assay				Bioorg Med Chem Lett 25: 1597-602 (2015) Article DOI: 10.1016/j.bmcl.2015.02.002 BindingDB Entry DOI: 10.7270/Q2HX1FBT
					More data for this Ligand-Target Pair