BDBM50065500 CHEMBL3402750

SMILES: Cc1cnc(s1)-c1cccc(Cn2nc(ccc2=O)-c2cc(F)cc(F)c2)c1

InChI Key: InChIKey=RBGXXGMNBFTAKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50065500 (CHEMBL3402750) Show SMILES Cc1cnc(s1)-c1cccc(Cn2nc(ccc2=O)-c2cc(F)cc(F)c2)c1 Show InChI InChI=1S/C21H15F2N3OS/c1-13-11-24-21(28-13)15-4-2-3-14(7-15)12-26-20(27)6-5-19(25-26)16-8-17(22)10-18(23)9-16/h2-11H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Research& Development Curated by ChEMBL					Assay Description Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assay				Bioorg Med Chem Lett 25: 1597-602 (2015) Article DOI: 10.1016/j.bmcl.2015.02.002 BindingDB Entry DOI: 10.7270/Q2HX1FBT
					More data for this Ligand-Target Pair