null
SMILES: Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45C(Oc1c24)c1[nH]c2c(cccc2c1C[C@@]35O)-c1ccccc1
InChI Key: InChIKey=PKDUVBIPSGHDLQ-OBSSAXLPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50065862 (22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranes | J Med Chem 41: 2872-81 (1998) Article DOI: 10.1021/jm980083i BindingDB Entry DOI: 10.7270/Q24F1RFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50065862 (22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor) | J Med Chem 41: 2872-81 (1998) Article DOI: 10.1021/jm980083i BindingDB Entry DOI: 10.7270/Q24F1RFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50065862 (22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranes | J Med Chem 41: 2872-81 (1998) Article DOI: 10.1021/jm980083i BindingDB Entry DOI: 10.7270/Q24F1RFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50065862 (22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ... | J Med Chem 41: 2872-81 (1998) Article DOI: 10.1021/jm980083i BindingDB Entry DOI: 10.7270/Q24F1RFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50065862 (22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranes | J Med Chem 41: 2872-81 (1998) Article DOI: 10.1021/jm980083i BindingDB Entry DOI: 10.7270/Q24F1RFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50065862 (22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 312 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites) | J Med Chem 41: 2872-81 (1998) Article DOI: 10.1021/jm980083i BindingDB Entry DOI: 10.7270/Q24F1RFN | |||||||||||
More data for this Ligand-Target Pair |