BDBM50065948 (2R,3S)-3-[(5-Chloro-1H-indole-2-carbonyl)-amino]-2-hydroxy-4-phenyl-butyric acid methyl ester::CHEMBL319854

SMILES: COC(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=YQHAEJPHUHNFSO-FUHWJXTLSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50065948 ((2R,3S)-3-[(5-Chloro-1H-indole-2-carbonyl)-amino]-...) Show SMILES COC(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C20H19ClN2O4/c1-27-20(26)18(24)16(9-12-5-3-2-4-6-12)23-19(25)17-11-13-10-14(21)7-8-15(13)22-17/h2-8,10-11,16,18,22,24H,9H2,1H3,(H,23,25)/t16-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against recombinant human liver glycogen phosphorylase a (rHLGPa) catalyzed release of phosphate from glucose-1-phosphat...				J Med Chem 41: 2934-8 (1998) Article DOI: 10.1021/jm980264k BindingDB Entry DOI: 10.7270/Q2NS0T1T
					More data for this Ligand-Target Pair