BDBM50066190 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-{[(S)-1-(benzyl-methyl-carbamoyl)-2-naphthalen-2-yl-ethyl]-amide} 1-[(2-methylcarbamoyl-phenyl)-amide]::CHEMBL419004

SMILES: CNC(=O)c1ccccc1NC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N(C)Cc1ccccc1

InChI Key: InChIKey=HOFQNBZCEZYVOE-CONSDPRKSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Substance-P receptor (Homo sapiens (Human))	BDBM50066190 ((S)-Pyrrolidine-1,2-dicarboxylic acid 2-{[(S)-1-(b...) Show SMILES CNC(=O)c1ccccc1NC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C35H37N5O4/c1-36-32(41)28-15-8-9-16-29(28)38-35(44)40-20-10-17-31(40)33(42)37-30(34(43)39(2)23-24-11-4-3-5-12-24)22-25-18-19-26-13-6-7-14-27(26)21-25/h3-9,11-16,18-19,21,30-31H,10,17,20,22-23H2,1-2H3,(H,36,41)(H,37,42)(H,38,44)/t30-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Medical Sciences Curated by ChEMBL					Assay Description In vitro binding affinity towards Tachykinin receptor 1 by measuring its ability to displace [3H]SP (0.6 nM) binding to membranes from Cos-7 cells tr...				J Med Chem 41: 3159-73 (1998) Article DOI: 10.1021/jm970499g BindingDB Entry DOI: 10.7270/Q2BZ66QJ
					More data for this Ligand-Target Pair
Substance-P receptor (GUINEA PIG)	BDBM50066190 ((S)-Pyrrolidine-1,2-dicarboxylic acid 2-{[(S)-1-(b...) Show SMILES CNC(=O)c1ccccc1NC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C35H37N5O4/c1-36-32(41)28-15-8-9-16-29(28)38-35(44)40-20-10-17-31(40)33(42)37-30(34(43)39(2)23-24-11-4-3-5-12-24)22-25-18-19-26-13-6-7-14-27(26)21-25/h3-9,11-16,18-19,21,30-31H,10,17,20,22-23H2,1-2H3,(H,36,41)(H,37,42)(H,38,44)/t30-,31-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Medical Sciences Curated by ChEMBL					Assay Description Tachykinin receptor 1 agonistic activity as inhibition of contractions evoked by 4 nM [Sar9,Met(O2)11]-SP in guinea pig ileum				J Med Chem 41: 3159-73 (1998) Article DOI: 10.1021/jm970499g BindingDB Entry DOI: 10.7270/Q2BZ66QJ
					More data for this Ligand-Target Pair