BDBM50066438 5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dione::CHEMBL283880

SMILES: Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O

InChI Key: InChIKey=URALYBWTMWGVCV-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50066438 (5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...) Show SMILES Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O Show InChI InChI=1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50066438 (5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...) Show SMILES Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O Show InChI InChI=1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50066438 (5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...) Show SMILES Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O Show InChI InChI=1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.				J Med Chem 41: 263-5 (1998) Article DOI: 10.1021/jm970624o BindingDB Entry DOI: 10.7270/Q24X5BJC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50066438 (5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...) Show SMILES Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O Show InChI InChI=1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50066438 (5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...) Show SMILES Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O Show InChI InChI=1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)				J Med Chem 41: 263-5 (1998) Article DOI: 10.1021/jm970624o BindingDB Entry DOI: 10.7270/Q24X5BJC
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50066438 (5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...) Show SMILES Cc1cccc(C)c1N1C(=O)c2ccc(N)cc2C1=O Show InChI InChI=1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line				Bioorg Med Chem Lett 9: 559-62 (1999) BindingDB Entry DOI: 10.7270/Q2ZW1MFX
					More data for this Ligand-Target Pair