BDBM50066831 CHEMBL3401612

SMILES: CCc1c([nH]c2ccc(Cl)cc12)C(=O)N1CCN(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=ADJAEKRETOSJPM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50066831 (CHEMBL3401612) Show SMILES CCc1c([nH]c2ccc(Cl)cc12)C(=O)N1CCN(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H21Cl2N3O/c1-2-17-18-13-15(23)5-8-19(18)24-20(17)21(27)26-11-9-25(10-12-26)16-6-3-14(22)4-7-16/h3-8,13,24H,2,9-12H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55940-induced calcium mobilization incubated fo...				Bioorg Med Chem 23: 2195-203 (2015) Article DOI: 10.1016/j.bmc.2015.02.058 BindingDB Entry DOI: 10.7270/Q29888PG
					More data for this Ligand-Target Pair