BDBM50066953 CHEMBL3403240

SMILES: Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OCCc1ccccc1

InChI Key: InChIKey=SIFWHILFECGYHK-WJDWOHSUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM50066953 (CHEMBL3403240) Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OCCc1ccccc1 Show InChI InChI=1S/C18H14BrNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h1-7,10-11H,8-9H2,(H,20,21,22)/b16-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of 15-PGDH (unknown origin) by fluorescence spectrophotometry				Bioorg Med Chem 23: 2098-103 (2015) Article DOI: 10.1016/j.bmc.2015.03.010 BindingDB Entry DOI: 10.7270/Q2NK3GR5
					More data for this Ligand-Target Pair