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BDBM50067639 2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3-{3-[(2-hydroxy-3-phenoxy-propyl)-methyl-amino]-propyl}-thiazolidin-4-one::CHEMBL344252

SMILES: CN(CCCN1C(SCC1=O)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)CC(O)COc1ccccc1

InChI Key: InChIKey=OIQRRPTWMZBNMA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067639   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium channel


(RAT)		BDBM50067639
PNG
(2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3-{3-[(2-hy...)
Show SMILES CN(CCCN1C(SCC1=O)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)CC(O)COc1ccccc1
Show InChI InChI=1S/C30H44N2O4S/c1-29(2,3)24-16-21(17-25(27(24)35)30(4,5)6)28-32(26(34)20-37-28)15-11-14-31(7)18-22(33)19-36-23-12-9-8-10-13-23/h8-10,12-13,16-17,22,28,33,35H,11,14-15,18-20H2,1-7H3
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Similars
Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Chugai Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of K+ induced contractions of the isolated rat aorta.

J Med Chem 41: 4309-16 (1998)


Article DOI: 10.1021/jm980335f
BindingDB Entry DOI: 10.7270/Q23N22JV
More data for this
Ligand-Target Pair