BDBM50067910 4,4'-Bis-dihydroxyboranyl-biphenyl::4,4'-biphenyldiboronic acid::CHEMBL109227::biphenyl-4,4'-diyldiboronic acid
SMILES: OB(O)c1ccc(cc1)-c1ccc(cc1)B(O)O
InChI Key: InChIKey=SLHKDOGTVUCXKX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta-lactamase AmpC (Escherichia coli) | BDBM50067910 (4,4'-Bis-dihydroxyboranyl-biphenyl | 4,4'-biphenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Binding affinity of the compound towards AmpC beta-lactamase binding site from Escherichia coli | J Med Chem 45: 3222-34 (2002) BindingDB Entry DOI: 10.7270/Q2CN737M | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-lactamase AmpC (Escherichia coli) | BDBM50067910 (4,4'-Bis-dihydroxyboranyl-biphenyl | 4,4'-biphenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Medical School Curated by ChEMBL | Assay Description Inhibitory activity against E. coli AmpC beta-lactamase. | J Med Chem 41: 4577-86 (1998) Article DOI: 10.1021/jm980343w BindingDB Entry DOI: 10.7270/Q22N51FX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |