BDBM50068234 5'-Chloro-1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one (4c)::CHEMBL2011865

SMILES: Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

InChI Key: InChIKey=KQTQQJVFFASAJD-UHFFFAOYSA-N

Data: 6 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50068234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells using seven compounds concentrations				Bioorg Med Chem Lett 25: 1827-30 (2015) Article DOI: 10.1016/j.bmcl.2015.03.049 BindingDB Entry DOI: 10.7270/Q2S46TNV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells at 0.1 and 1 uM				Bioorg Med Chem Lett 25: 1827-30 (2015) Article DOI: 10.1016/j.bmcl.2015.03.049 BindingDB Entry DOI: 10.7270/Q2S46TNV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human cloned 5-HT1A receptor expressed in HEK293 cells at 0.1 and 1 uM				Bioorg Med Chem Lett 25: 1827-30 (2015) Article DOI: 10.1016/j.bmcl.2015.03.049 BindingDB Entry DOI: 10.7270/Q2S46TNV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells using seven compounds concentrations				Bioorg Med Chem Lett 25: 1827-30 (2015) Article DOI: 10.1016/j.bmcl.2015.03.049 BindingDB Entry DOI: 10.7270/Q2S46TNV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human cloned 5-HT7R expressed in HEK293 cells at 0.1 and 1 uM				Bioorg Med Chem Lett 25: 1827-30 (2015) Article DOI: 10.1016/j.bmcl.2015.03.049 BindingDB Entry DOI: 10.7270/Q2S46TNV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells at 0.1 and 1 uM				Bioorg Med Chem Lett 25: 1827-30 (2015) Article DOI: 10.1016/j.bmcl.2015.03.049 BindingDB Entry DOI: 10.7270/Q2S46TNV
					More data for this Ligand-Target Pair
Probable maltase-glucoamylase 2 (Homo sapiens)	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Babasaheb Bhimrao Ambedkar University (A Central University) Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...				Eur J Med Chem 176: 343-377 (2019) Article DOI: 10.1016/j.ejmech.2019.04.025
					More data for this Ligand-Target Pair
alpha-Glucosidase (alpha-Glu) (Saccharomyces cerevisiae)	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair